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Heterodimeric integrin complexes containing β1-integrin promote internalization and lethality of anthrax toxin
To kill macrophages, the lethal factor component of Bacillus anthracis toxin binds to a carrier protein (PA), which then interacts with the CMG2 receptor protein on the cell surface and is endocytosed into the cytoplasm. CMG2, as well as TEM8, a second PA receptor not present on macrophages, contain...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932583/ https://ncbi.nlm.nih.gov/pubmed/20713715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010145107 |
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