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Structural Conservation Predominates Over Sequence Variability in the Crown of HIV Type 1's V3 Loop

The diversity of HIV-1 is a confounding problem for vaccine design, as the human immune response appears to favor poor or strain-specific responses to any given HIV-1 virus strain. A significant portion of this diversity is manifested as sequence variability in the loops of HIV-1's surface enve...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Almond, David, Kimura, Tetsuya, Kong, XiangPeng, Swetnam, James, Zolla-Pazner, Susan, Cardozo, Timothy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932551/
https://ncbi.nlm.nih.gov/pubmed/20560796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2009.0254
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