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Nitric Oxide in the Vasculature: Where Does It Come From and Where Does It Go? A Quantitative Perspective

Nitric oxide (NO) affects two key aspects of O(2) supply and demand: It regulates vascular tone and blood flow by activating soluble guanylate cyclase (sGC) in the vascular smooth muscle, and it controls mitochondrial O(2) consumption by inhibiting cytochrome c oxidase. However, significant gaps exi...

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Detalhes bibliográficos
Main Authors: Chen, Kejing, Pittman, Roland N., Popel, Aleksander S.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932548/
https://ncbi.nlm.nih.gov/pubmed/18331202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2007.1959
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