GPR55 ligands promote receptor coupling to multiple signalling pathways

BACKGROUND AND PURPOSE: Although GPR55 is potently activated by the endogenous lysophospholipid, L-α-lysophosphatidylinositol (LPI), it is also thought to be sensitive to a number of cannabinoid ligands, including the prototypic CB1 receptor antagonists AM251 and SR141716A (Rimonabant®). In this stu...

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Detalhes bibliográficos
Main Authors: Henstridge, Christopher M, Balenga, Nariman AB, Schröder, Ralf, Kargl, Julia K, Platzer, Wolfgang, Martini, Lene, Arthur, Simon, Penman, June, Whistler, Jennifer L, Kostenis, Evi, Waldhoer, Maria, Irving, Andrew J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931561/
https://ncbi.nlm.nih.gov/pubmed/20136841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00625.x
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