A genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron disease

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that, for ∼80% of patients, is fatal within five years of diagnosis. To better understand ALS, animal models have been essential; however, only rodent models of ALS exhibit the major hallmarks of the disease. Here, we re...

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Detalhes bibliográficos
Main Authors: Ramesh, Tennore, Lyon, Alison N., Pineda, Ricardo H., Wang, Chunping, Janssen, Paul M. L., Canan, Benjamin D., Burghes, Arthur H. M., Beattie, Christine E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2010
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Resource Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931540/
https://ncbi.nlm.nih.gov/pubmed/20504969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.005538
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