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CCL2 is induced by chemotherapy and protects prostate cancer cells from docetaxel - induced cytotoxicity

BACKGROUND: Metastatic prostate cancer is either inherently resistant to chemotherapy or rapidly acquires this phenotype after chemotherapy exposure. In this study, we identified a docetaxel-induced resistance mechanism centered on CCL2. METHODS: we compared the gene expression profiles in individua...

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Bibliografiske detaljer
Main Authors: Qian, David Z., Rademacher, Brooks L.S., Pittsenbarger, Janet, Huang, Chung-Ying, Myrthue, Anne, Higano, Celestia S., Garzotto, Mark, Nelson, Peter S., Beer, Tomasz M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931415/
https://ncbi.nlm.nih.gov/pubmed/19866475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21077
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