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Late signals from CD27 prevent Fas dependent apoptosis of primary CD8+ T cells

The role of costimulation has previously been confined to the very early stages of the CD8+ T cell response. In this study we demonstrate the requirement for CD27 costimulation during the later phase but not programming of the primary CD8+ T cell response to Influenza virus and reveal a novel mechan...

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Autors principals: Dolfi, Douglas V., Boesteanu, Alina C., Petrovas, Constantinos, Xia, Dong, Butz, Eric A., Katsikis, Peter D.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931327/
https://ncbi.nlm.nih.gov/pubmed/18292513
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