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Induction of mucosal immunity in the avian Harderian gland with a replication-deficient Ad5 vector expressing avian influenza H5 hemagglutinin

The chicken Harderian gland (HG) plays an important role in adaptive immune responses upon ocular exposure to avian pathogens such as avian influenza (AI). To determine the role of HGs in generating immunity, chickens were immunized ocularly with an adenovirus (Ad5) vector expressing the AI hemagglu...

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Autori principali: van Ginkel, Frederik W., Tang, De-chu C., Gulley, Stephen L., Toro, Haroldo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931278/
https://ncbi.nlm.nih.gov/pubmed/18773917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dci.2008.07.018
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