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The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation

Human cytomegalovirus (HCMV) encodes an endoplasmic reticulum (ER)-resident transmembrane glycoprotein, US10, expressed early in the replicative cycle of HCMV as part of the same cluster that encodes the known immunoevasins US2, US3, US6, and US11. We show that US10 down-regulates cell surface expre...

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Sonraí Bibleagrafaíochta
Main Authors: Park, Boyoun, Spooner, Eric, Houser, Brandy L., Strominger, Jack L., Ploegh, Hidde L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931171/
https://ncbi.nlm.nih.gov/pubmed/20713594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091793
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