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Fatty acid modulation and polyamine block of GluK2 kainate receptors analyzed by scanning mutagenesis

RNA editing of kainate receptor subunits at the Q/R site determines their susceptibility to inhibition by cis-unsaturated fatty acids as well as block by cytoplasmic polyamines. Channels comprised of unedited (Q) subunits are strongly blocked by polyamines, but insensitive to fatty acids, such as ar...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wilding, Timothy J., Chen, Kevin, Huettner, James E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931155/
https://ncbi.nlm.nih.gov/pubmed/20805577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010442
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