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Lapatinib in the Treatment of Hormone Receptor-Positive/ErbB2-Positive Breast Cancer

SUMMARY: In women with estrogen receptor(ER)- and ErbB2 (HER2)-positive breast cancer, a vicious cycle is established between ER mechanisms of action and the growth factor receptor network, leading to enhanced cell proliferation and endocrine resistance. As such, co-targeting ErbB1 and ErbB2 with la...

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Bibliografische gegevens
Hoofdauteurs: Bauerfeind, Ingo, Elling, Dirk, Heinemann, Volker
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: S. Karger GmbH 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931095/
https://ncbi.nlm.nih.gov/pubmed/20847831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000285775
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