Loss of the Y chromosome in Philadelphia-positive cells predicts a poor response of chronic myeloid leukemia patients to imatinib mesylate therapy

In chronic myeloid leukemia (CML), cytogenetic abnormalities found in addition to the t(9;22) translocation may impact the response to therapy. Loss of the Y chromosome is generally overlooked in this context, owing to its relatively frequent occurrence in healthy elderly patients. In this multicent...

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Bibliografische gegevens
Hoofdauteurs: Lippert, Eric, Etienne, Gabriel, Mozziconacci, Marie-Joelle, Laibe, Sophy, Gervais, Carine, Girault, Stéphane, Gachard, Nathalie, Tigaud, Isabelle, Dastugue, Nicole, Huguet, François, Fort, Marie-Pierre, Legros, Laurence, Eclache, Virginie, Mahon, Francois-Xavier
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ferrata Storti Foundation 2010
Onderwerpen:
Brief Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930965/
https://ncbi.nlm.nih.gov/pubmed/20435623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.019109
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