Colon OCTN2 Gene Expression Is Up-regulated by Peroxisome Proliferator-activated Receptor γ in Humans and Mice and Contributes to Local and Systemic Carnitine Homeostasis

In the large intestine organic cation transporter type-2 (OCTN2) is recognized as a transporter of compounds such as carnitine and colony sporulation factor, promoting health of the colon intestinal epithelium. Recent reports suggest that OCTN2 expression in small intestine is under control of perox...

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Autors principals: D'Argenio, Giuseppe, Petillo, Orsolina, Margarucci, Sabrina, Torpedine, Angela, Calarco, Anna, Koverech, Angela, Boccia, Angelo, Paolella, Giovanni, Peluso, Gianfranco
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930707/
https://ncbi.nlm.nih.gov/pubmed/20558736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.109678
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