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Iron and Porphyrin Trafficking in Heme Biogenesis

Iron is an essential element for diverse biological functions. In mammals, the majority of iron is enclosed within a single prosthetic group: heme. In metazoans, heme is synthesized via a highly conserved and coordinated pathway within the mitochondria. However, iron is acquired from the environment...

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Autori principali: Schultz, Iman J., Chen, Caiyong, Paw, Barry H., Hamza, Iqbal
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930673/
https://ncbi.nlm.nih.gov/pubmed/20522548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R110.119503
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