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Nanoconjugation modulates the trafficking and mechanism of antibody induced receptor endocytosis

Treatment with monoclonal antibody (mAbs) is a viable therapeutic option in cancer. Recently, these mAbs such as cetuximab, herceptin, etc., have been used as targeting agents to selectively deliver chemotherapeutics to cancerous cells. However, mechanisms of nanoparticles-mAbs interactions with the...

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Autores principales: Bhattacharyya, Sanjib, Bhattacharya, Resham, Curley, Steven, McNiven, Mark A., Mukherjee, Priyabrata
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930461/
https://ncbi.nlm.nih.gov/pubmed/20679244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006507107
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