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Efficient reprogramming of adult neural stem cells to monocytes by ectopic expression of a single gene

Neural stem cells have a broad differentiation repertoire during embryonic development and can be reprogrammed to pluripotency comparatively easily. We report that adult neural stem cells can be reprogrammed at very high efficiency to monocytes, a differentiated fate of an unrelated somatic lineage,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Forsberg, Magda, Carlén, Marie, Meletis, Konstantinos, Yeung, Maggie S. Y., Barnabé-Heider, Fanie, Persson, Mats A. A., Aarum, Johan, Frisén, Jonas
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930460/
https://ncbi.nlm.nih.gov/pubmed/20675585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009412107
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