Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

In several murine models of autoimmune arthritis, Th17 cells are the dominant initiators of inflammation. In human arthritis the majority of IL-17–secreting cells within the joint express a cytokine phenotype intermediate between Th17 and Th1. Here we show that Th17/1 cells from the joints of childr...

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Detalhes bibliográficos
Main Authors: Nistala, Kiran, Adams, Stuart, Cambrook, Helen, Ursu, Simona, Olivito, Biagio, de Jager, Wilco, Evans, Jamie G., Cimaz, Rolando, Bajaj-Elliott, Mona, Wedderburn, Lucy R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930428/
https://ncbi.nlm.nih.gov/pubmed/20679229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003852107
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