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An Alternative Conformation of the T-Cell Receptor α Constant Region

αβ T-cell receptors (TcRs) play a central role in cellular immune response. They are members of the Ig superfamily, with extracellular regions of the α and β chains each comprising a V-type domain and a C-type domain. We have determined the ectodomain structure of an αβ TcR, which recognizes the aut...

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Hlavní autoři: van Boxel, Gijs I., Holmes, Samantha, Fugger, Lars, Jones, E. Yvonne
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930249/
https://ncbi.nlm.nih.gov/pubmed/20630474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.05.053
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