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Murine models of Alzheimer's disease and their use in developing immunotherapies

Alzheimer's disease (AD) is one of the categories of neurodegenerative diseases characterized by a conformational change of a normal protein into a pathological conformer with a high β-sheet content that renders it resistant to degradation and neurotoxic. In AD, the normal soluble amyloid β (sA...

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Main Authors: Wisniewski, Thomas, Sigurdsson, Einar M.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930136/
https://ncbi.nlm.nih.gov/pubmed/20471477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2010.05.004
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