CCR2 Plays a Critical Role in Dendritic Cell Maturation: Possible Role of CCL2 and NF-κB

We postulated that CCR2-driven activation of the transcription factor NF-κB plays a critical role in dendritic cell (DC) maturation (e.g., migration, costimulation, and IL-12p70 production), necessary for the generation of protective immune responses against the intracellular pathogen Leishmania maj...

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Detalhes bibliográficos
Main Authors: Jimenez, Fabio, Quinones, Marlon P., Martinez, Hernan G., Estrada, Carlos A., Clark, Kassandra, Garavito, Edgar, Ibarra, Jessica, Melby, Peter C., Ahuja, Seema S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929965/
https://ncbi.nlm.nih.gov/pubmed/20404272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803494
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