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Light-dependant intraretinal ion regulation by melanopsin in young awake and free moving mice evaluated with manganese-enhanced MRI

PURPOSE: To test the hypothesis that in young, functionally blind mice, light-dependent intraretinal ion regulation occurs via melanopsin. METHODS: Postnatal day (P) 7 wild type (WT, C57Bl/6) and melanopsin knockout (KO, opn4−/−, B6129) mice were light or dark adapted. Awake and freely moving animal...

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Autors principals: Berkowitz, Bruce A., Roberts, Robin, Bissig, David
Format: Artigo
Idioma:Inglês
Publicat: Molecular Vision 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929942/
https://ncbi.nlm.nih.gov/pubmed/20808732
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