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Synthesis of the bis-tetrahydropyran Core of Amphidinol 3

[Image: see text] A convergent synthesis of the C31-C52 bis-tetrahydropyran core of the natural product amphidinol 3 is reported. A common intermediate was synthesized from D-tartaric acid utilizing an asymmetric glycolate alkylation/ring-closing metathesis sequence to construct the THP rings. Diffe...

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Detalhes bibliográficos
Main Authors: Crimmins, Michael T., Martin, Timothy J., Martinot, Theodore A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929927/
https://ncbi.nlm.nih.gov/pubmed/20795745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol1015898
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