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Ethyl pyruvate inhibits hypoxic pulmonary vasoconstriction and attenuates pulmonary artery cytokine expression

Hypoxic pulmonary vasoconstriction is a common consequence of acute lung injury and may be mediated by increased local production of proinflammatory cytokines. Ethyl pyruvate is a novel anti-inflammatory agent that has been shown to downregulate proinflammatory genes following hemorrhagic shock; how...

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Detalhes bibliográficos
Main Authors: Tsai, Ben M., Lahm, Tim, Morrell, Eric D., Crisostomo, Paul R., Markel, Troy, Wang, Meijing, Meldrum, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929586/
https://ncbi.nlm.nih.gov/pubmed/17574585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2007.03.067
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