Neuroimaging Enrichment Strategy for Secondary Prevention Trials in Alzheimer’s Disease

We examined the improvement in statistical power that could be obtained in therapeutic trials for early (pre-dementia) Alzheimer’s disease (AD) by constraining enrollment to individuals with amnestic mild cognitive impairment (MCI) and an atrophy pattern on a screening MRI previously found to be pre...

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Detalhes bibliográficos
Main Authors: McEvoy, L.K., Edland, S.D., Holland, D., Hagler, D.J., Roddey, J.C., Fennema-Notestine, C., Salmon, D.P., Koyama, A.K., Aisen, P.S., Brewer, J.B., Dale, A.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929320/
https://ncbi.nlm.nih.gov/pubmed/20683184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WAD.0b013e3181d1b814
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