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Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture
Freshly isolated muscle stem cells (MuSCs) exhibit robust regenerative capacity in vivo that is rapidly lost in culture. Using a bioengineered substrate to recapitulate key biophysical and biochemical niche features in conjunction with a novel highly automated single cell tracking algorithm, we show...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929271/ https://ncbi.nlm.nih.gov/pubmed/20647425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1191035 |
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