Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture

Freshly isolated muscle stem cells (MuSCs) exhibit robust regenerative capacity in vivo that is rapidly lost in culture. Using a bioengineered substrate to recapitulate key biophysical and biochemical niche features in conjunction with a novel highly automated single cell tracking algorithm, we show...

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Detaylı Bibliyografya
Asıl Yazarlar: Gilbert, PM, Havenstrite, KL, Magnusson, KEG, Sacco, A, Leonardi, NA, Kraft, P, Nguyen, NK, Thrun, S, Lutolf, MP, Blau, HM
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929271/
https://ncbi.nlm.nih.gov/pubmed/20647425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1191035
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