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Variant alleles of the CYP1B1 gene are associated with colorectal cancer susceptibility

BACKGROUND: CYP1B1 is a P450 enzyme which is involved in the activation of pro-carcinogens to carcinogens as well as sex hormone metabolism. Because differences in the activity of the enzyme have been correlated with variant alleles of single nucleotide polymorphisms (SNPs), it represents an attract...

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Detalhes bibliográficos
Main Authors: Trubicka, Joanna, Grabowska-Kłujszo, Ewa, Suchy, Janina, Masojć, Bartłomiej, Serrano-Fernandez, Pablo, Kurzawski, Grzegorz, Cybulski, Cezary, Górski, Bohdan, Huzarski, Tomasz, Byrski, Tomasz, Gronwald, Jacek, Złowocka, Elżbieta, Kładny , Józef, Banaszkiewicz, Zbigniew, Wiśniowski, Rafał, Kowalska, Elżbieta, Lubinski, Jan, Scott, Rodney J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929240/
https://ncbi.nlm.nih.gov/pubmed/20701755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-420
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