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Elucidation of the conformational free energy landscape in H.pylori LuxS and its implications to catalysis
BACKGROUND: One of the major challenges in understanding enzyme catalysis is to identify the different conformations and their populations at detailed molecular level in response to ligand binding/environment. A detail description of the ligand induced conformational changes provides meaningful insi...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929236/ https://ncbi.nlm.nih.gov/pubmed/20704697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-10-27 |
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