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Elucidation of the conformational free energy landscape in H.pylori LuxS and its implications to catalysis

BACKGROUND: One of the major challenges in understanding enzyme catalysis is to identify the different conformations and their populations at detailed molecular level in response to ligand binding/environment. A detail description of the ligand induced conformational changes provides meaningful insi...

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Autors principals: Bhattacharyya, Moitrayee, Vishveshwara, Saraswathi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929236/
https://ncbi.nlm.nih.gov/pubmed/20704697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-10-27
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