CC Chemokine Ligand 3 Overcomes the Bacteriocidal and Phagocytic Defect of Macrophages and Hastens Recovery from Experimental Otitis Media in TNF(−/−) Mice

Innate immune mechanisms are crucial in defense against bacterial illnesses in humans, as evidenced by abnormal antibacterial responses due to defects in TLR signaling, seen in children with MyD88 or IL-1R–associated kinase 4 deficiency. Otitis media (OM) is the most common disease of childhood, and...

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Hauptverfasser: Leichtle, Anke, Hernandez, Michelle, Ebmeyer, Joerg, Yamasaki, Kenshi, Lai, Yuping, Radek, Katherine, Choung, Yun-Hoon, Euteneuer, Sara, Pak, Kwang, Gallo, Richard, Wasserman, Stephen I., Ryan, Allen F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929161/
https://ncbi.nlm.nih.gov/pubmed/20164426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901167
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