Candesartan reduces the innate immune response to lipopolysaccharide in human monocytes

OBJECTIVE: Inhibition of angiotensin II receptor type 1 (AT(1)) reduces chronic inflammation associated with hypertension. We asked whether AT(1) receptor inhibition would reduce the innate inflammatory response induced by bacterial lipopolysaccharide (LPS). METHODS: We used unstimulated human circu...

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Hlavní autoři: Larrayoz, Ignacio M., Pang, Tao, Benicky, Julius, Pavel, Jaroslav, Sánchez-Lemus, Enrique, Saavedra, Juan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928995/
https://ncbi.nlm.nih.gov/pubmed/19730394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e3283314bc7
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