Osteopontin Mediates Citrobacter rodentium-Induced Colonic Epithelial Cell Hyperplasia and Attaching-Effacing Lesions

Although osteopontin (OPN) is up-regulated in inflammatory bowel diseases, its role in disease pathogenesis remains controversial. The objective of this study was to determine the role of OPN in host responses to a non-invasive bacterial pathogen, Citrobacter rodentium, which serves as a murine infe...

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Detalhes bibliográficos
Main Authors: Wine, Eytan, Shen-Tu, Grace, Gareau, Mélanie G., Goldberg, Harvey A., Licht, Christoph, Ngan, Bo-Yee, Sorensen, Esben S., Greenaway, James, Sodek, Jaro, Zohar, Ron, Sherman, Philip M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928965/
https://ncbi.nlm.nih.gov/pubmed/20651246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091068
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