Synovial fluid of patients with rheumatoid arthritis induces α-smooth muscle actin in human adipose tissue-derived mesenchymal stem cells through a TGF-β1-dependent mechanism

Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. Transforming growth factor-β1 (TGF-β1) is a secreted protein that promotes differentiation of synovial fibroblasts to α-smooth muscle actin (α-SMA)-positive myofibroblasts to...

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Bibliographische Detailangaben
Hauptverfasser: Song, Hae Young, Kim, Min Young, Kim, Kyung Hye, Lee, Il Hwan, Shin, Sang Hun, Lee, Jung Sub, Kim, Jae Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Biochemistry and Molecular Biology 2010
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928929/
https://ncbi.nlm.nih.gov/pubmed/20628268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.8.057
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