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Genetic Analysis of Baker's Yeast Msh4-Msh5 Reveals a Threshold Crossover Level for Meiotic Viability

During meiosis, the Msh4-Msh5 complex is thought to stabilize single-end invasion intermediates that form during early stages of recombination and subsequently bind to Holliday junctions to facilitate crossover formation. To analyze Msh4-Msh5 function, we mutagenized 57 residues in Saccharomyces cer...

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Autori principali: Nishant, K. T., Chen, Cheng, Shinohara, Miki, Shinohara, Akira, Alani, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928781/
https://ncbi.nlm.nih.gov/pubmed/20865162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001083
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