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A Phenomenological Model for Predicting Melting Temperatures of DNA Sequences

We report here a novel method for predicting melting temperatures of DNA sequences based on a molecular-level hypothesis on the phenomena underlying the thermal denaturation of DNA. The model presented here attempts to quantify the energetic components stabilizing the structure of DNA such as base p...

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Detalhes bibliográficos
Main Authors: Khandelwal, Garima, Bhyravabhotla, Jayaram
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928768/
https://ncbi.nlm.nih.gov/pubmed/20865157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012433
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