Elg1, an alternative subunit of the RFC clamp loader, preferentially interacts with SUMOylated PCNA

Replication-factor C (RFC) is a protein complex that loads the processivity clamp PCNA onto DNA. Elg1 is a conserved protein with homology to the largest subunit of RFC, but its function remained enigmatic. Here, we show that yeast Elg1 interacts physically and genetically with PCNA, in a manner tha...

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Main Authors: Parnas, Oren, Zipin-Roitman, Adi, Pfander, Boris, Liefshitz, Batia, Mazor, Yuval, Ben-Aroya, Shay, Jentsch, Stefan, Kupiec, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928695/
https://ncbi.nlm.nih.gov/pubmed/20571511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.128
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