A possible mechanism for ezrin to establish epithelial cell polarity

Ezrin is an important membrane/actin cytoskeleton linker protein, especially in epithelia. Ezrin has two important binding domains: an NH(2)-terminal region that binds to plasma membrane and a COOH-terminal region that binds to F-actin only after a conformational activation by phosphorylation at Thr...

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Detalhes bibliográficos
Main Authors: Zhu, Lixin, Crothers, James, Zhou, Rihong, Forte, John G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Protein and Vesicle Trafficking, Cytoskeleton
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928635/
https://ncbi.nlm.nih.gov/pubmed/20505040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00090.2010
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