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Dicarboxylate carrier-mediated glutathione transport is essential for reactive oxygen species homeostasis and normal respiration in rat brain mitochondria

Glutathione transport into mitochondria is mediated by oxoglutarate (OGC) and dicarboxylate carrier (DIC) in the kidney and liver. However, transport mechanisms in brain mitochondria are unknown. We found that both carriers were expressed in the brain. Using cortical mitochondria incubated with phys...

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Detalhes bibliográficos
Main Authors: Kamga, Christelle K., Zhang, Shelley X., Wang, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928630/
https://ncbi.nlm.nih.gov/pubmed/20538765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00058.2010
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