μ-Opioid receptor stimulation in the medial subnucleus of the tractus solitarius inhibits gastric tone and motility by reducing local GABA activity

We examined the effects of altering μ-opioid receptor (MOR) activity in the medial subnucleus of the tractus solitarius (mNTS) on several gastric end points including intragastric pressure (IGP), fundus tone, and the receptive relaxation reflex (RRR). Microinjection of the MOR agonist [d-Ala(2),MePh...

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Detalhes bibliográficos
Main Authors: Herman, Melissa A., Alayan, Alisa, Sahibzada, Niaz, Bayer, Barbara, Verbalis, Joseph, Dretchen, Kenneth L., Gillis, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Neuroregulation and Motility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928531/
https://ncbi.nlm.nih.gov/pubmed/20489046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00038.2010
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