μ-Opioid receptor stimulation in the medial subnucleus of the tractus solitarius inhibits gastric tone and motility by reducing local GABA activity

We examined the effects of altering μ-opioid receptor (MOR) activity in the medial subnucleus of the tractus solitarius (mNTS) on several gastric end points including intragastric pressure (IGP), fundus tone, and the receptive relaxation reflex (RRR). Microinjection of the MOR agonist [d-Ala(2),MePh...

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Bibliografische gegevens
Hoofdauteurs: Herman, Melissa A., Alayan, Alisa, Sahibzada, Niaz, Bayer, Barbara, Verbalis, Joseph, Dretchen, Kenneth L., Gillis, Richard A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2010
Onderwerpen:
Neuroregulation and Motility
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928531/
https://ncbi.nlm.nih.gov/pubmed/20489046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00038.2010
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