μ-Opioid receptor stimulation in the medial subnucleus of the tractus solitarius inhibits gastric tone and motility by reducing local GABA activity

We examined the effects of altering μ-opioid receptor (MOR) activity in the medial subnucleus of the tractus solitarius (mNTS) on several gastric end points including intragastric pressure (IGP), fundus tone, and the receptive relaxation reflex (RRR). Microinjection of the MOR agonist [d-Ala(2),MePh...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Herman, Melissa A., Alayan, Alisa, Sahibzada, Niaz, Bayer, Barbara, Verbalis, Joseph, Dretchen, Kenneth L., Gillis, Richard A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2010
Pynciau:
Neuroregulation and Motility
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928531/
https://ncbi.nlm.nih.gov/pubmed/20489046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00038.2010
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