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An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer

Genome-wide association studies (GWAS) routinely identify risk variants in noncoding DNA, as exemplified by reports of multiple single nucleotide polymorphisms (SNPs) associated with prostate cancer in five independent regions in a gene desert on 8q24. Two of these regions also have been associated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wasserman, Nora F., Aneas, Ivy, Nobrega, Marcelo A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928497/
https://ncbi.nlm.nih.gov/pubmed/20627891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.105361.110
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