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The BDNF Val66Met Polymorphism, Hippocampal Volume and Cognitive Function in Geriatric Depression

OBJECTIVE: The Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene is associated with geriatric depression. In studies of younger adults without depression, met allele carriers exhibit smaller hippocampal volumes and have poorer performance on neuropsychological tests. We exam...

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Détails bibliographiques
Auteurs principaux: Benjamin, Sophiya, McQuoid, Douglas R., Potter, Guy G., Payne, Martha E., MacFall, James R., Steffens, David C., Taylor, Warren D.
Format: Artigo
Langue:Inglês
Publié: 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928477/
https://ncbi.nlm.nih.gov/pubmed/20220593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JGP.0b013e3181cabd2b
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