Specific shRNA targeting of FAK influenced collagen metabolism in rat hepatic stellate cells

AIM: To investigate the effects and mechanism of disruption of focal adhesion kinase (FAK) expression on collagen metabolism in rat hepatic stellate cells (HSC). METHODS: The plasmids expressing FAK short hairpin RNA (shRNA) were transfected into HSC-T6 cells, and the level of FAK expression was det...

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Bibliografski detalji
Glavni autori: Dun, Zhi-Na, Zhang, Xiao-Lan, An, Jun-Yan, Zheng, Li-Bo, Barrett, Robert, Xie, Shu-Rui
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Co., Limited 2010
Teme:
Brief Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928467/
https://ncbi.nlm.nih.gov/pubmed/20731027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i32.4100
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