Linkage Specific Fucosylation of Alpha-1-Antitrypsin in Liver Cirrhosis and Cancer Patients: Implications for a Biomarker of Hepatocellular Carcinoma

BACKGROUND: We previously reported increased levels of protein-linked fucosylation with the development of liver cancer and identified many of the proteins containing the altered glycan structures. One such protein is alpha-1-antitrypsin (A1AT). To advance these studies, we performed N-linked glycan...

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Главные авторы: Comunale, Mary Ann, Rodemich-Betesh, Lucy, Hafner, Julie, Wang, Mengjun, Norton, Pamela, Di Bisceglie, Adrian M., Block, Timothy, Mehta, Anand
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928295/
https://ncbi.nlm.nih.gov/pubmed/20811639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012419
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