Characterization of BRCA1 and BRCA2 Deleterious Mutations and Variants of Unknown Clinical Significance in Unilateral and Bilateral Breast Cancer: The WECARE Study

BRCA1 and BRCA2 screening in women at high-risk of breast cancer results in the identification of both unambiguously defined deleterious mutations and sequence variants of unknown clinical significance (VUS). We examined a population-based sample of young women with contralateral breast cancer (CBC,...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Borg, Åke, Haile, Robert W., Malone, Kathleen E., Capanu, Marinela, Diep, Ahn, Törngren, Therese, Teraoka, Sharon, Begg, Colin B., Thomas, Duncan C., Concannon, Patrick, Mellemkjaer, Lene, Bernstein, Leslie, Tellhed, Lina, Xue, Shanyan, Olson, Eric R., Liang, Xiaolin, Dolle, Jessica, Børresen-Dale, Anne-Lise, Bernstein, Jonine L.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928257/
https://ncbi.nlm.nih.gov/pubmed/20104584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.21202
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires