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Characterization of the chemotactic and mitogenic response of SMCs to PDGF-BB and FGF-2 in fibrin hydrogels

The delivery of growth factors to cellularize biocompatible scaffolds like fibrin is a commonly used strategy in tissue engineering. We characterized SMC proliferation and chemotaxis in response to PDGF-BB and FGF-2, alone and in combination, in 2-D culture and in 3-D fibrin hydrogels. While both gr...

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Détails bibliographiques
Auteurs principaux: Ucuzian, Areck A., Brewster, Luke P., East, Andrea T., Pang, Yongang, Gassman, Andrew A., Greisler, Howard P.
Format: Artigo
Langue:Inglês
Publié: 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928161/
https://ncbi.nlm.nih.gov/pubmed/20730936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.32786
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