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Overexpression and activation of epidermal growth factor receptor in hemangioblastomas

Hemangioblastomas frequently develop in patients with von Hippel-Lindau (VHL) disease, an autosomal dominant genetic disorder. The tumors are characterized by a dense network of blood capillaries, often in association with cysts. Although activation of receptor tyrosine kinase (RTK) signaling, inclu...

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Detalhes bibliográficos
Main Authors: Chen, Gregory J., Karajannis, Matthias A., Newcomb, Elizabeth W., Zagzag, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928155/
https://ncbi.nlm.nih.gov/pubmed/20730556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-010-0125-9
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