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Interaction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degeneration

Defects in biogenesis or function(s) of primary cilia are associated with numerous inherited disorders (called ciliopathies) that may include retinal degeneration phenotype. The cilia-expressed gene RPGR (retinitis pigmentosa GTPase regulator) is mutated in patients with X-linked retinitis pigmentos...

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Autori principali: Murga-Zamalloa, Carlos A., Atkins, Stephen J., Peranen, Johan, Swaroop, Anand, Khanna, Hemant
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928130/
https://ncbi.nlm.nih.gov/pubmed/20631154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq275
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