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Interaction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degeneration

Defects in biogenesis or function(s) of primary cilia are associated with numerous inherited disorders (called ciliopathies) that may include retinal degeneration phenotype. The cilia-expressed gene RPGR (retinitis pigmentosa GTPase regulator) is mutated in patients with X-linked retinitis pigmentos...

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Detalhes bibliográficos
Main Authors: Murga-Zamalloa, Carlos A., Atkins, Stephen J., Peranen, Johan, Swaroop, Anand, Khanna, Hemant
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928130/
https://ncbi.nlm.nih.gov/pubmed/20631154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq275
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