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PLDLS-dependent interaction of E1A with CtBP: regulation of CtBP nuclear localization and transcriptional functions
C-terminal binding proteins (CtBPs) are cellular corepressors that are targeted by adenovirus E1A. A conserved motif of E1A (PLDLS) interacts with an N-terminal hydrophobic cleft of CtBPs. Many cellular cofactors also interact with CtBPs through PLDLS-like motifs. E1A interaction with CtBP2 changed...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928068/ https://ncbi.nlm.nih.gov/pubmed/17546044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210569 |
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