CTLA4 Variants, UV-Induced Tolerance, and Risk of Non-Melanoma Skin Cancer

Although skin tumors are highly immunogenic, exposure to UV radiation is known to suppress immune responses via regulatory T cells. Specifically, the activity of cytotoxic lymphocyte-associated antigen-4 (CTLA-4) is integral in regulating the development of UV-induced tolerance and, concomitantly, s...

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Bibliographic Details
Main Authors: Welsh, Marleen M., Applebaum, Katie M., Spencer, Steven K., Perry, Ann E., Karagas, Margaret R., Nelson, Heather H.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928067/
https://ncbi.nlm.nih.gov/pubmed/19622768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0415
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