Assessing sources of inconsistencies in genotypes and their effects on genome-wide association studies with HapMap samples

The discordance in results of independent genome-wide association studies (GWAS) indicates the potential for Type I and Type II errors. We assessed the repeatibility of current Affymetrix technologies that support GWAS. Reasonable reproducibility was observed for both raw intensity and the genotypes...

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Hlavní autoři: Hong, H, Shi, L, Su, Z, Ge, W, Jones, W D, Czika, W, Miclaus, K, Lambert, C G, Vega, S C, Zhang, J, Ning, B, Liu, J, Green, B, Xu, L, Fang, H, Perkins, R, Lin, S M, Jafari, N, Park, K, Ahn, T, Chierici, M, Furlanello, C, Zhang, L, Wolfinger, R D, Goodsaid, F, Tong, W
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928027/
https://ncbi.nlm.nih.gov/pubmed/20368714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2010.24
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