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Lipid activation of the signal recognition particle receptor provides spatial coordination of protein targeting

The signal recognition particle (SRP) and SRP receptor comprise the major cellular machinery that mediates the cotranslational targeting of proteins to cellular membranes. It remains unclear how the delivery of cargos to the target membrane is spatially coordinated. We show here that phospholipid bi...

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Detalhes bibliográficos
Main Authors: Lam, Vinh Q., Akopian, David, Rome, Michael, Henningsen, Doug, Shan, Shu-ou
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928010/
https://ncbi.nlm.nih.gov/pubmed/20733058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201004129
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