Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

Tissue stiffening is a hallmark of fibrotic disorders but has traditionally been regarded as an outcome of fibrosis, not a contributing factor to pathogenesis. In this study, we show that fibrosis induced by bleomycin injury in the murine lung locally increases median tissue stiffness sixfold relati...

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Bibliografiska uppgifter
Huvudupphovsmän: Liu, Fei, Mih, Justin D., Shea, Barry S., Kho, Alvin T., Sharif, Asma S., Tager, Andrew M., Tschumperlin, Daniel J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2010
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928007/
https://ncbi.nlm.nih.gov/pubmed/20733059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201004082
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